Meta-analysis of epidemiological studies of association of P53 codon 72 polymorphism with bladder cancer.

@article{Li2010MetaanalysisOE,
  title={Meta-analysis of epidemiological studies of association of P53 codon 72 polymorphism with bladder cancer.},
  author={Dongxu Li and X Wei and L H Jiang and Yisi Wang and Fei Xu},
  journal={Genetics and molecular research : GMR},
  year={2010},
  volume={9 3},
  pages={1599-605}
}
Although there have been many studies investigating a possible association between p53 codon 72 polymorphism and risk of bladder cancer, the results have been inconsistent. We conducted a meta-analysis of six epidemiological studies, which included 597 bladder cancer cases and 731 controls. Patients with bladder cancer had a significantly lower frequency of Pro/Arg [odds ratio (OR) = 0.80, 95% confidence interval (CI) = 0.64-0.99], when compared to controls. Stratifying for race, we found that… CONTINUE READING

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