Meta-analysis of calcineurin-inhibitor-sparing regimens in kidney transplantation.

  title={Meta-analysis of calcineurin-inhibitor-sparing regimens in kidney transplantation.},
  author={Adnan Sharif and Shazia Shabir and Sourabh Chand and Paul Cockwell and Simon Ball and Richard J Borrows},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={22 11},
Calcineurin-inhibitor-sparing strategies in kidney transplantation may spare patients the adverse effects of these drugs, but the efficacy of these strategies is unknown. Here, we conduct a meta-analysis to assess outcomes associated with reducing calcineurin inhibitor exposure from the time of transplantation. We search Medline, Embase, and Cochrane Register of Controlled Trials for randomized controlled trials published between 1966 and 2010 that compared de novo calcineurin-inhibitor-sparing… CONTINUE READING
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