Meta-analysis of acute lung injury and acute respiratory distress syndrome trials testing low tidal volumes.

@article{Eichacker2002MetaanalysisOA,
  title={Meta-analysis of acute lung injury and acute respiratory distress syndrome trials testing low tidal volumes.},
  author={Peter Q Eichacker and Eric P Gerstenberger and Steven M. Banks and Xizhong Cui and C Natanson},
  journal={American journal of respiratory and critical care medicine},
  year={2002},
  volume={166 11},
  pages={
          1510-4
        }
}
The use of low tidal volumes (5-7 ml/kg measured body weight) as a protective lung strategy is becoming widely recommended for patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) requiring mechanical ventilation (1-4). However, clinical trials testing low tidal volumes in ALI and ARDS have not shown uniform results (5-7). This has led some experts to recommend avoiding high tidal volumes during mechanical ventilation in these patients (6, 8), whereas other… CONTINUE READING

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