Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

@article{Lanktree2011MetaanalysisOD,
  title={Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.},
  author={M. Lanktree and Yiran Guo and M. Murtaza and J. Glessner and Swneke D. Bailey and N. Onland-Moret and G. Lettre and H. Ongen and R. Rajagopalan and T. Johnson and Haiqing Shen and C. Nelson and N. Klopp and J. Baumert and S. Padmanabhan and N. Pankratz and J. Pankow and Sonia Shah and K. Taylor and J. Barnard and Bas J. M. Peters and C. M. Maloney and M. Lobmeyer and A. Stanton and M. Zafarmand and S. Romaine and A. Mehta and E. V. van Iperen and Y. Gong and Tom S. Price and Erin N. Smith and Cecilia Kim and Y. Li and F. Asselbergs and L. Atwood and K. Bailey and Deepak L. Bhatt and F. Bauer and E. Behr and T. Bhangale and J. Boer and B. Boehm and J. Bradfield and Morris J. Brown and P. Braund and P. Burton and C. Carty and Hareesh R. Chandrupatla and W. Chen and J. Connell and Chrysoula Dalgeorgou and A. Boer and F. Drenos and C. Elbers and James C. Fang and C. Fox and E. Frackelton and B. Fuchs and C. Furlong and Q. Gibson and C. Gieger and A. Goel and D. Grobbee and C. Hastie and Philip J Howard and Guan-hua Huang and W. C. Johnson and Qing Li and M. Kleber and B. Klein and R. Klein and C. Kooperberg and B. Ky and A. LaCroix and P. Lanken and M. Lathrop and Mingyao Li and V. Marshall and O. Melander and F. Mentch and N. Meyer and K. Monda and A. Montpetit and G. Murugesan and K. Nakayama and D. Nondahl and A. Onipinla and S. Rafelt and S. Newhouse and F. Otieno and S. R. Patel and M. Putt and S. Rodr{\'i}guez and Radwan N Safa and D. Sawyer and P. Schreiner and C. Simpson and S. Sivapalaratnam and S. Srinivasan and C. Suver and G. Swergold and N. Sweitzer and Kelly A Thomas and B. Thorand and N. Timpson and Sam E. Tischfield and M. Tobin and M. Tomaszewski and W. Verschuren and C. Wallace and B. Winkelmann and Haitao Zhang and D. Zheng and L. Zhang and J. Zmuda and R. Clarke and A. Balmforth and J. Danesh and I. Day and N. Schork and P. D. de Bakker and C. Delles and D. Duggan and A. Hingorani and J. Hirschhorn and M. Hofker and S. Humphries and M. Kivimaki and D. Lawlor and K. Kottke-Marchant and J. Mega and B. Mitchell and D. Morrow and J. Palmen and S. Redline and D. Shields and A. Shuldiner and P. Sleiman and George Davey Smith and M. Farrall and Y. Jamshidi and D. Christiani and J. Casas and A. Hall and P. Doevendans and J. Christie and G. Berenson and S. Murray and T. Illig and G. Dorn and T. Cappola and E. Boerwinkle and P. Sever and D. Rader and M. Reilly and M. Caulfield and P. Talmud and E. Topol and J. Engert and K. Wang and A. Dominiczak and A. Hamsten and S. Curtis and R. Silverstein and L. Lange and M. Sabatine and M. Trip and D. Saleheen and J. Peden and K. Cruickshanks and W. M{\"a}rz and J. O'Connell and O. Klungel and C. Wijmenga and A. H. Maitland-van der Zee and E. Schadt and Julie A. Johnson and G. Jarvik and G. Papanicolaou and S. Grant and P. Munroe and K. North and N. Samani and W. Koenig and Tom R. Gaunt and Sonia S Anand and Y. T. van der Schouw and N. Soranzo and G. FitzGerald and A. Reiner and R. Hegele and H. Hakonarson and B. Keating},
  journal={American journal of human genetics},
  year={2011},
  volume={88 1},
  pages={
          6-18
        }
}
Height is a classic complex trait with common variants in a growing list of genes known to contribute to the phenotype. Using a genecentric genotyping array targeted toward cardiovascular-related loci, comprising 49,320 SNPs across approximately 2000 loci, we evaluated the association of common and uncommon SNPs with adult height in 114,223 individuals from 47 studies and six ethnicities. A total of 64 loci contained a SNP associated with height at array-wide significance (p < 2.4 × 10(-6… Expand
A rare variant in COL11A1 is strongly associated with adult height in Chinese Han population.
  • C. Shen, X. Zheng, +17 authors F. Zhou
  • Biology, Medicine
  • Journal of genetics and genomics = Yi chuan xue bao
  • 2016
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Rare and low-frequency coding variants alter human adult height
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
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