Meta-analysis identifies tumor necrosis factor-alpha and interleukin-1 beta as diagnostic biomarkers for bacterial and aseptic meningitis.

@article{Panato2014MetaanalysisIT,
  title={Meta-analysis identifies tumor necrosis factor-alpha and interleukin-1 beta as diagnostic biomarkers for bacterial and aseptic meningitis.},
  author={Ana Paula Ronzani Panato and Luiza Trajano Tomasi and Carla Sasso Simon and Kristian Madeira and Lutiana Roque Sim{\~o}es and Lidia Rosi de Freitas Medeiros and Tatiana Barichello and Maria In{\^e}s da Rosa},
  journal={Current neurovascular research},
  year={2014},
  volume={11 4},
  pages={
          340-8
        }
}
BACKGROUND Meningitis is a complex and severe acute infectious disease of the central nervous system and is caused mainly by bacteria and viruses. However, the distinction between aseptic and bacterial meningitis can be difficult for clinicians because the symptoms and the results of laboratory assays are often similar and overlapping, particularly when the use of antibiotics is administered prior to examining the cerebrospinal fluid. METHODS We determined the accuracy of tumor necrosis… CONTINUE READING