Meta-analysis: risk of fractures with acid-suppressing medication.

  title={Meta-analysis: risk of fractures with acid-suppressing medication.},
  author={Chun Shing Kwok and Jessica Ka-Yan Yeong and Y K Loke},
  volume={48 4},
AIMS Recent studies have suggested an increased risk of fractures with proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs). We planned to perform a meta-analysis of fractures in patients taking PPIs and H2RAs. METHODS We searched MEDLINE and EMBASE in September 2010 for observational studies reporting on the risk of fractures with acid-suppressing medication (PPIs and H2RA). We also checked the references lists of included studies and regulatory authority websites for… CONTINUE READING


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