Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation

@article{Hart2007MetaanalysisAT,
  title={Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation},
  author={R. Hart and L. Pearce and M. Aguilar},
  journal={Annals of Internal Medicine},
  year={2007},
  volume={146},
  pages={857-867}
}
Context Thirteen new randomized, controlled trials are available since a 1999 meta-analysis of antithrombotic agents for stroke prevention in patients with atrial fibrillation. Contribution This updated meta-analysis shows that, compared with placebo, adjusted-dose warfarin reduces stroke risk by 64% (6 trials) and antiplatelet agents reduce stroke risk by 22% (8 trials). Meta-analysis of 12 trials shows that adjusted-dose warfarin is more effective than antiplatelet therapy, but it doubles the… Expand
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Paper Mentions

Interventional Clinical Trial
The primary objective is to demonstrate the safety and efficacy of the implantation of the LAmbreTM device in patients with large or irregularly shaped appendages with non-valvular… Expand
ConditionsAtrial Fibrillation, CVA, Left Atrial Appendage Thrombosis
InterventionDevice
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This study aims to compare the effectiveness and safety regarding treatment with standard anticoagulant only or adding antiplatelet to anticoagulant in patients with non-valvular… Expand
ConditionsAcute Ischemic Stroke, Anticoagulant, Antiplatelet, (+5 more)
InterventionDrug
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ConditionsNew Onset Atrial Fibrillation
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