Corpus ID: 2488269

Meta-Analysis Effects of Intravenous and Oral Magnesium on Reducing Migraine : A Meta-analysis of Randomized Controlled Trials

  title={Meta-Analysis Effects of Intravenous and Oral Magnesium on Reducing Migraine : A Meta-analysis of Randomized Controlled Trials},
  author={Hsiao-Yean Chiu and Tu-Hsueh Yeh and Yin-Cheng Huang and Pin-Yuan Chen},
Results: A total of 21 studies were included. Of which, 11 studies investigated the effects of intravenous magnesium on acute migraine (948 participants) and 10 examined the effects of oral magnesium on migraine prophylaxis (789 participants). Intravenous magnesium significantly relieved acute migraine within 15 – 45 minutes, 120 minutes, and 24 hours after the initial infusion (Odd ratios [ORs] = 0.23, 0.20, and 0.25, respectively). Oral magnesium significantly alleviated the frequency and… Expand

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