Meta-Analysis: Does Garlic Intake Reduce Risk of Gastric Cancer?

@article{Kodali2015MetaAnalysisDG,
  title={Meta-Analysis: Does Garlic Intake Reduce Risk of Gastric Cancer?},
  author={Ramyasri Kodali and Guy D. Eslick},
  journal={Nutrition and Cancer},
  year={2015},
  volume={67},
  pages={1 - 11}
}
In the past 2 decades, various epidemiological studies investigated whether garlic can positively modify the risk of gastric cancer. Garlic contains numerous sulfide compounds, including diallyl trisulfide, which have anticarcinogenic properties. We conducted a meta-analysis to determine if garlic intake reduces the risk of gastric cancer. An electronic search of MEDLINE, PubMed, and EMBASE to June 2014 was completed. There were 14 case control studies, 2 randomized controlled studies, and 1… Expand
Comparative assessment of the antibacterial profile of Onion (Allium cepa) and Garlic (Allium sativum) against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans
Aqueous and ethanol extracts of onion and garlic were evaluated for antibacterial susceptibility profile using disc dilution method. Each extract was evaluated at concentrations of 100%, 50% 25% andExpand
Open access in silico tools to predict the ADMET profiling and PASS (Prediction of Activity Spectra for Substances of Bioactive compounds of Garlic (Allium sativum L.)
TLDR
This work investigated the main bioactive components of garlic through a bioinformatics approach, and established an open-access database to determine the ADMET attributes of garlic molecules and to enable identification of promising molecules that follow ADMET properties. Expand
The Potential Application of Allium Extracts in the Treatment of Gastrointestinal Cancers
TLDR
The aim of this review was to present and discuss currently investigated Allium extracts and their effects on several gastrointestinal cancers including gastric, colon, liver, esophageal, and pancreatic cancer. Expand
Types of garlic and their anticancer and antioxidant activity: a review of the epidemiologic and experimental evidence
TLDR
The aim of the review is to provide an overview of the different types of garlic, their active compounds, and the potential anticancer benefits with a focus on antioxidant activity. Expand
Bidirect effects from cisplatin combine with rosmarinic acid (RA) or hot water extracts of Glechoma hederacea (HWG) on renal cancer cells
TLDR
It is proposed that the inhibition of RA on RCC 786-O cell invasion and migration may partly occur through the downregulation of FAK phosphorylation, and the HWG/CDDP and RA/ CDDP combined treatments may be effective strategies for intervention of R CC 786 -O cell activity. Expand
The Potential for Reducing Lynch Syndrome Cancer Risk with Nutritional Nrf2 Activators
TLDR
It is hypothesized that nutritional Nrf2 activators may have the potential to reduce the risk of cancer in those with LS by modulating OS and inflammation. Expand
Allium vegetable consumption and health: An umbrella review of meta‐analyses of multiple health outcomes
Abstract Previously, our meta‐analysis and other studies have suggested that allium vegetable consumption is beneficial for health, but no umbrella review has been conducted to assess the evidence ofExpand
Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.)
TLDR
Overall, garlic is an excellent natural source of bioactive sulfur-containing compounds and has promising applications in the development of functional foods or nutraceuticals for the prevention and management of certain diseases. Expand
C18H17NO6 and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression
TLDR
C18H17NO6 could efficiently suppress cell proliferation and induce cell apoptosis in glioma cells, and its combination with Scutellarin had a promoting effect, in which the underlying mechanism referred to the upregulation of Fas-associated factor 1. Expand
Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity
TLDR
The results indicate the potential application of Allium genus to GC chemoprevention and treatment support through CDH restoration and COX2 downregulation and it is possible that tumours with increasedCOX2 expression will be more susceptible to garlic treatment. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 36 REFERENCES
Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.
TLDR
Garlic and vitamin treatments were associated with non-statistically significant reductions in gastric cancer incidence and mortality and vitamin treatment was associated with statistically significantly fewer deaths from gastric or esophageal cancer, a secondary endpoint. Expand
An intervention study to prevent gastric cancer by micro-selenium and large dose of allitridum.
TLDR
The present study proves that large doses of allitridum and microdorse of selenium may effectively prevent gastric cancer, especially in men. Expand
A meta-analysis of body mass index and esophageal and gastric cardia adenocarcinoma.
TLDR
Overweight and obesity are strongly related to EGCA, particularly to espophageal adenocarcinoma, as well as normo-weight subjects, using random-effects models. Expand
CA: A
  • Cancer statistics
  • 2013
Cancer statistics, 2013
TLDR
Overall cancer death rates have declined 20% from their peak in 1991 to 2009 and can be accelerated by applying existing cancer control knowledge across all segments of the population, with an emphasis on those groups in the lowest socioeconomic bracket and other underserved populations. Expand
Australian Institute of Health and Welfare & Australasian Association of Cancer Registries: Cancer in Australia: an overview
  • 2012
Evaluation of dietary and life-style habits of patients with gastric cancer: a case-control study in Turkey.
TLDR
Improved dietary habits, reducing salt consumption and eradication of H. pylori infection may provide protection against gastric cancer in Turkey. Expand
Global cancer statistics
TLDR
A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake. Expand
...
1
2
3
4
...