Meta‐analysis: antioxidant supplements for primary and secondary prevention of colorectal adenoma

@article{Bjelakovic2006MetaanalysisAS,
  title={Meta‐analysis: antioxidant supplements for primary and secondary prevention of colorectal adenoma},
  author={Goran Bjelakovic and Aleksandar V. Nagorni and Dimitrinka Nikolova and Rosa Giovanna Simonetti and Marija Dakovi{\'c} Bjelakovi{\'c} and Christian Gluud},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2006},
  volume={24}
}
Colorectal cancer may be prevented by reducing the development of adenomatous polyps. 
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Meta‐analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer
Aliment Pharmacol Ther 31, 708–718
Systematic review: primary and secondary prevention of gastrointestinal cancers with antioxidant supplements
TLDR
The evidence on whether antioxidant supplements prevent gastrointestinal cancers is contradictory and further research is needed to establish a causal relationship between antioxidant supplements and gastrointestinal cancers. Expand
Review article: nutrition, obesity and colorectal cancer
TLDR
A large number of patients in prosperous industrialized countries with a high age-adjusted incidence of colorectal cancer are diagnosed with at least some types of cancer, but the mechanisms remain obscure. Expand
Antioxidants in the chemoprevention of colorectal cancer and colorectal adenomas in the general population: a systematic review and meta‐analysis
  • D. Papaioannou, K. Cooper, +4 authors R. Logan
  • Medicine
  • Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • 2011
TLDR
This review aimed to assess the present evidence on the effect of antioxidants on the incidence of colorectal neoplasms in the general population. Expand
Selenium in the prevention of colorectal cancer
TLDR
The limited clinical data suggest a potential benefit of selenium supplementation, however, more conclusive evidence is needed before any dietary recommendation can be decided. Expand
Do antioxidants prevent colorectal cancer? A meta-analysis.
  • R. Pais, D. Dumitrascu
  • Medicine
  • Romanian journal of internal medicine = Revue roumaine de medecine interne
  • 2013
TLDR
This meta-analysis found no evidence in favor of a protective effect of the studied antioxidant supplements in the prevention of colorectal cancer or cancer related mortality. Expand
Chemoprevention of Colorectal Cancer.
TLDR
This work reviews the prospect of chemoprevention of CRC, results from preclinical and human studies, challenges, and future directions, and suggests agents that might be used for average-risk as well as high-risk groups, and to prevent colorectal cancer recurrence after therapy. Expand
Updates on Translational Research on Prevention of Polyps and Colorectal Cancer.
  • E. Stoffel
  • Medicine
  • Clinics in colon and rectal surgery
  • 2018
TLDR
This review will present an overview of strategies for primary and secondary prevention of CRC, including endoscopic, pharmacologic, and dietary interventions. Expand
Antioxidant supplements for preventing gastrointestinal cancers.
TLDR
Assessing the beneficial and harmful effects of antioxidant supplements in preventing gastrointestinal cancers could not find convincing evidence that antioxidant supplements prevent gastrointestinal cancers. Expand
Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis.
TLDR
Assessment of the evidence for the effectiveness of calcium in reducing the recurrence of adenomas and the occurrence of colorectal cancer among populations at high, intermediate, and low risk of the disease indicated that supplemental calcium was effective for the prevention ofadenoma recurrence in populations with a history ofAdenomas, but no similar effect was apparent in populations at higher or lower risk. Expand
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References

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