Meta‐analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding – an updated Cochrane review

@article{ChavezTapia2011MetaanalysisAP,
  title={Meta‐analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding – an updated Cochrane review},
  author={Norberto Chavez-Tapia and Tonatiuh Barrientos-Guti{\'e}rrez and F{\'e}lix Ignacio T{\'e}llez-{\'A}vila and Karla Soares-Weiser and Nah{\'u}m M{\'e}ndez-S{\'a}nchez and Christian Gluud and Misael Uribe},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2011},
  volume={34}
}
Aliment Pharmacol Ther 2011; 34: 509–518 
Antibiotic Prophylaxis in Patients with Cirrhosis and Upper Gastrointestinal Bleeding.
TLDR
Antibiotics should be used for prophylaxis in hospitalized patients with cirrhosis and upper gastrointestinal bleeding to reduce all-cause mortality and bacterial infections and rebleeding. Expand
The role of antibiotics in upper gastrointestinal bleeding among cirrhotic patients without major complications after endoscopic hemostasis
TLDR
Comparison of clinical outcomes between cirrhotic patients without major complications with UGIB with and without antibiotic prophylaxis aimed to compare the clinical outcomes. Expand
A French national survey on the use of antibiotic prophylaxis in cirrhotic patients
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Guidelines recommend antibiotic prophylaxis (AP) in well‐selected groups of cirrhotic patients, but the impact of these recommendations has not been assessed in France.
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TLDR
This poster focuses on the treatment of acute upper gastrointestinal bleeding in patients with a history of central giant cell granuloma or GBM. Expand
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TLDR
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Portal hypertension in patients with liver cirrhosis is the main factor contributing to the formation of esophageal or gastric varices. The risk of bleeding reflects the grade of portal hypertensionExpand
Prevalence and in‐hospital mortality trends of infections among patients with cirrhosis: a nationwide study of hospitalised patients in the United States
Data on bacterial infections in hospitalised patients in the US with cirrhosis are derived largely from single centre data. Countrywide data in this population are lacking.
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TLDR
In cirrhotic patients with gastrointestinal bleeding, short‐term antibiotic prophylaxis significantly increases the mean percentage of patients free of infection and significantly increases short-term survival rate. Expand
Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding.
TLDR
Prophylactic antibiotic use in patients with cirrhosis and upper gastrointestinal bleeding significantly reduced bacterial infections, and seems to have reduced all-cause mortality, bacterial infection mortality, rebleeding events, and hospitalisation length. Expand
Prophylactic antibiotics in cirrhotics with upper gastrointestinal hemorrhage: a prospective, controlled trial.
TLDR
The authors' prophylactic antibiotic treatment proved safe and effective in reducing the infection rate in cirrhotics with upper gastrointestinal bleeding. Expand
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Prophylactic intestinal decontamination with oral ciprofloxacin is effective in the prevention of bacterial infections in patients with cirrhosis who were suffering from acute upper gastrointestinal hemorrhage. Expand
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TLDR
Antibiotic prophylaxis for cirrhotic inpatients with gastrointestinal bleeding is efficacious in reducing the number of deaths and bacterial infections, are well tolerated, and should be advocated. Expand
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TLDR
Patients with a Child‐Pugh's class C and/or a rebleeding are a subgroup of cirrhotic patients with a high risk of infection after gastrointestinal hemorrhage and in these patients, a prophylactic treatment with systemic antibiotics is very effective in preventing bacterial infections. Expand
Systemic antibiotic therapy prevents bacterial infection in cirrhotic patients with gastrointestinal hemorrhage
This randomized prospective study was aimed at assessing the efficiency of a systemic antibiotic therapy for the prevention of bacterial infections in cirrhotic patients with gastrointestinalExpand
Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: A randomized trial
TLDR
In conclusion, antibiotic prophylaxis can prevent infection and rebleeding as well as decrease the amount of blood transfused for patients with acute GEVB following endoscopic treatment. Expand
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The results show that selective intestinal decontamination with norfloxacin is useful in preventing bacterial infections in cirrhotic patients with gastrointestinal hemorrhage. Expand
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TLDR
In cirrhotic patients with variceal bleeding and with Child-Pugh class B or C, the use of intravenous ciprofloxacin for 3 days after EVL was not only effective in the prevention of bacterial infections but also cost-effective. Expand
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