Meta‐Analysis of Natural Therapies for Hyperlipidemia: Plant Sterols and Stanols versus Policosanol

@article{Chen2005MetaAnalysisON,
  title={Meta‐Analysis of Natural Therapies for Hyperlipidemia: Plant Sterols and Stanols versus Policosanol},
  author={Judy T. Chen and Robert A. Wesley and Robert D. Shamburek and Frank Pucino and Gyorgy Csako},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2005},
  volume={25}
}
Study Objective. To compare the efficacy and safety of plant sterols and stanols as well as policosanol in the treatment of coronary heart disease, as measured by a reduction in low‐density lipoprotein cholesterol (LDL) levels. 
Lipid lowering effect of policosanol and omega-3 fatty acids combined therapy in hypercholesterolemic patients
Resumen es: Aunque el colesterol de las lipoproteinas de baja densidad (LDL-C) continua siendo el principal objetivo en el manejo de la dislipidemia, la prevencion d...
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Phytosterols for dyslipidemia.
  • J. M. Malinowski, M. Gehret
  • Medicine, Biology
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
  • 2010
TLDR
Overall, phytosterols are useful for reducing LDL cholesterol in patients who cannot reach their treatment goal by diet alone or who are taking maximum tolerated doses of statins.
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  • Medicine
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  • 2019
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It is well established that a higher level of serum HDL-cholesterol is associated with lower incidence of coronary artery disease and increased longevity and it has been reported that consumption of PCO can significantly reduce serum total cholesterol and LDL-ch cholesterol levels as well as raise serum cholesterol levels.
Evaluation of cholesterol-lowering and antioxidant properties of sugar cane policosanols in hamsters and humans
TLDR
The aim of this thesis project was first to compare the composition and cholesterol-lowering effects of different SCP preparations in hamsters, and second to test the cholesterol- Lowering efficacy, mechanism of action, and antioxidant capacity of original SCPs in humans.
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Effect of policosanol on lipid levels among patients with hypercholesterolemia or combined hyperlipidemia: a randomized controlled trial.
TLDR
In patients with hypercholesterolemia or combined hyperlipidemia, the sugar cane-derived policosanol in usual and high doses does not demonstrate a reduction in lipid levels beyond placebo.
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