Met-enkephalin-like immunoreactivity in a cephalopod neurohemal organ

  title={Met-enkephalin-like immunoreactivity in a cephalopod neurohemal organ},
  author={R. Mart{\'i}n and D. Frōsch and Eckard Weber and Frederick Voigt},
  journal={Neuroscience Letters},
Occurrence of immunoreactive enkephalins in a neurohemal organ and other nervous structures in the eyestalk of the shore crab, Carcinus maenas L. (Crustacea, Decapoda)
SummaryLight-microscopical observations with immunofluorescence and peroxidase staining procedures revealed leu-enkephalin-like immunoreactivity in axon profiles of the sinus gland (SG) and in single
Immunocytochemical localization of a methionine‐enkephalin‐resembling neuropeptide in the central nervous system of the american cockroach, Periplaneta americana L
Within the brain and retrocerebral complex of Periplaneta americana several neuronal structures which were very specifically stained with an anti‐methionine‐enkephalin antiserum are demonstrated, presenting new evidence for the recently developed concept that opiate peptides, identical or related to those found in higher species, occur also in invertebrates.
Differential localization of leu-enkephalin and hyperglycemic hormone in axon terminals of the sinus gland of the crabsCarcinus maenas, eriocheir sinensis, andUca pugilator
Leu-enkephalin containing secretory granules were demonstrated in axon terminals of immunogoldlabeled electron-microscopic sections of the sinus gland of three brachyuran crustaceans and a modulatory activity of endogenous enkephaline by paracrine mechanisms is suggested.
Enkephalins, Biologically Active Neuropeptides in Invertebrates, with Special Reference to Crustaceans
In vivo and in vitro studies support the view that endogenous enkephalin inhibits the exocytotic release of the hyperglycemic neurohormone from the sinus gland.
Enkephalin-like immunoreactivity in the pedal ganglion of Mytilus edulis (Bivalvia) and its proximity to dopamine-containing structures
The closeness of enkephalin-like immunoreactivity to dopamine histofluorescence supports previous data demonstrating biochemical and physiological links between these two systems.
Immunohistochemical localization of opioid peptides in the brain of the leech Theromyzon tessulatum
No correspondence could be established between the neurons containing met- or leu-enkephalin-like substances and the different types of neurosecretory cells classically described in Hirudinea.
Mapping of enkephalin-related peptides in the nervous system of the blowfly, Calliphora vomitoria, and their co-localization with cholecystokinin (CCK)- and pancreatic polypeptide (PP)-like peptides
The enkephalin-like immunoreactive material of certain neurons identified within the brain and thoracic ganglion shows a complex pattern of co-existence with pancreatic polypeptide- and gastrin/cholecystokinin-like peptides.
Immunohistological evidence of methionine enkephalin-like material in the brain of the migratory locust
The topographic distribution of these met-enkephalin arborizations suggests that these four neurons may act as neuromodulators of the acitivity of the major neurosecretory cells in the brain of this insect.


Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm
The authors' finding of nerves storing immunoreactive enkephalin or β-endorphin in the earthworm is reported, and this species is thought to lack endogenous opiate receptors.
Pituitary somatotrophs contain [Met]enkephalin-like immunoreactivity.
  • E. Weber, K. Voigt, R. Martín
  • Biology, Medicine
    Proceedings of the National Academy of Sciences of the United States of America
  • 1978
Serial sections from epoxy resin-embedded rat anterior pituitaries were sequentially immunostained for endorphin, [Met]enkephalin, and growth hormone, respectively and suggested that somatotrophs synthesize [ met]enkphalin in somatOTrophs, but this cannot be proved conclusively until biosynthesis experiments have been performed.
alpha-Neo-endorphin : a "big" Leu-enkephalin with potent opiate activity from porcine hypothalami.
Evidence for two separate opiate peptide neuronal systems
WHEN Hughes et al.1 first described the sequences of the enkephalins, they pointed out that methionine–enkephalin (met-enkephalin) could be found in β-lipotropin (β-LPH 61–65). The entire C-terminal
The neurosecretory system of the vena cava in Cephalopoda II. Sepia officinalis and Octopus vulgaris
A system of nerves (called for short NSV system) described previously in Eledone cirrosa, whose only task appears to be the formation of a fine neuropile in the vena cava, is present also in Sepia officinalis and shows certain special features.
Analysis of the common precursor to corticotropin and endorphin.
The structure of this common precursor molecule was determined by using a number of different techniques to examine the radiolabeled corticotropinand endorphin-containing molecules secreted by tumor cells incubated with labeled amino acids or sugars.
Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary.
The results show that brain endorphin levels are independent of pituitary endorphIn levels; they suggest that beta-endorphin-containing neurons and those containing enkephalin constitute two separate groups of brain cells.
Existence of a common precursor to ACTH and endorphin in the anterior and intermediate lobes of the rat pituitary.
Extracts of rat anterior and intermediate-posterior pituitary were fractionated by sodium dodecyl sulfate polyacrylamide gel electrophoresis and assayed for immunoactive ACTH and endorphin. In both
The Neurosecretory System of the Vena Cava In Cephalopoda I. Eledone Cirrosa
The disposition of the elements of this system is peculiar in that the axons of the cells situated in the caudal prolongations of the ganglionic trunks must run far rostralwards until they reach the nerves to which they contribute.