Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density.

@article{PoznerMoulis2006MetTH,
  title={Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density.},
  author={Sharon Pozner-Moulis and Derek J Pappas and David L. Rimm},
  journal={Cancer research},
  year={2006},
  volume={66 16},
  pages={7976-82}
}
Some breast cancer cases in our previous immunohistochemical studies show Met expression in the nucleus. Given nuclear localization of other receptor tyrosine kinases, we proceeded to investigate Met. Nuclear Met is seen in numerous cell lines and in germinal regions of many tissues using four unique antibodies. Cell fractionation reveals a 60-kDa band recognized by COOH-terminal Met antibodies that is present independent of hepatocyte growth factor treatment. Green fluorescent protein (GFP… CONTINUE READING