Mesothelioma in Cappadocian Villages

@article{Dogan2003MesotheliomaIC,
  title={Mesothelioma in Cappadocian Villages},
  author={A. Dogan},
  journal={Indoor and Built Environment},
  year={2003},
  volume={12},
  pages={367 - 375}
}
  • A. Dogan
  • Published 2003
  • Geography
  • Indoor and Built Environment
Volcanic tuffs in the Cappadocian region of Turkey have weathered into a dramatic landscape. The soft rock of which they are composed is easily quarried and excavated and has long provided both caves and building material for homes. Studying the complex geology of Cappadocia has shown the presence of zeolitic rocks in some areas which contain respirable fibres of the zeolite group mineral erionite. In 1975, a high incidence of malignant pleural mesothelioma (MPM) was observed in several… Expand

Tables from this paper

Zeolite Mineralogy and Cappadocian Erionite
The discovery some 30 years ago that erionite, a fibrous zeolite mineral, induced mesotheliomas in those living in certain villages in Cappadocia engendered a vast amount of bothExpand
Prospective study of mesothelioma mortality in Turkish villages with exposure to fibrous zeolite.
TLDR
The results emphasize the severity of the mesothelioma endemic in erionite-exposed areas of Turkey and call for intensified prevention of mesot helioma by limiting environmental exposures to these fibers. Expand
Erionite exposure in North Dakota and Turkish villages with mesothelioma
TLDR
The findings indicate that implementation of novel preventive and early detection programs in ND and other erionite-rich areas of the United States, similar to efforts currently being undertaken in Turkey, is warranted. Expand
Erionite series minerals: mineralogical and carcinogenic properties
TLDR
Micro morphological details of erionite minerals using a high-resolution field-emission SEM showed that microstructures of “bundles’, “fibers”, and ”fibrils” are important physical properties of fibrous erionites, and their relationship to the carcinogenicity of the mineral is drawn attention. Expand
Malignant Mesothelioma and Erionite
TLDR
Advances in genetics, biochemistry, and molecular biology have begun to allow some insight into what was happening when a normal cell was changed into a cancerous one and often why it happened, and cancer research has concentrated on the identification of environmental and occupational causes of human cancer. Expand
Airborne asbestos fibres and mesothelioma in the last 20 years in Egypt: a review
Abstract Asbestos has been used in Egypt ever since 2000 – 3000 BC for embalming the bodies of Egyptian pharaohs. Little data is available on airborne asbestos fibre counts in the occupational andExpand
Asbestos Mineralogy and Health Effects
TLDR
The key questions concern whether or not, and to what extent, exposure to chrysotile asbestos, including its natural contaminant tremolite, causes mesothelioma. Expand
RECENT TRENDS IN THE MANAGEMENT OF MESOTHELIOMA - A RARE FORM OF CANCER: A REVIEW
TLDR
Treatment for mesothelioma depends on the location of the cancer, the stage of the disease, and the patient's age and general health, and standard treatment options include surgery, radiation therapy, and chemotherapy. Expand
Quantitative characterization of the mesothelioma-inducing erionite series minerals by transmission electron microscopy and energy dispersive spectroscopy.
TLDR
Air-collected erionite series minerals from Cappadocia region of Turkey were characterized quantitatively by using transmission electron microscopy (TEM) equipped with energy dispersive spectroscopy (EDS) and a mean chemical formula is proposed based upon the TEM-EDS results. Expand
Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres.
TLDR
The present findings demonstrate for the first time the presence of pleural plaques in the lungs of subjects exposed to fluoro-edenite fibres, and not to asbestos, through residing in Biancavilla and through their occupation. Expand
...
1
2
...

References

SHOWING 1-10 OF 68 REFERENCES
Zeolite occurrences and the erionite-mesothelioma relationship in Cappadocia, central Anatolia, Turkey
Cappadocia is essentially covered by nine rhyolitic ignimbrite units, being the products of a multi-phase volcanism of Upper Miocene-Pliocene age. Around Ürgüp and the Kizilirmak River, theseExpand
Zeolite Mineralogy and Cappadocian Erionite
The discovery some 30 years ago that erionite, a fibrous zeolite mineral, induced mesotheliomas in those living in certain villages in Cappadocia engendered a vast amount of bothExpand
Erionite exposure and mesotheliomas in rats.
TLDR
Experimental studies using both intrapleural inoculation and inhalation techniques with erionite from this region and from Oregon in the United States demonstrate that there is a valuable new fibre for experimental study and a possible hazard to man in regions other then Turkey. Expand
Malignant mesotheliomas in a small village in the Anatolian region of Turkey: an epidemiologic study.
TLDR
An epidemiologic and cause-related study was done in Tuzköy, a small village in the city of Nevşehir, in the Anatolian region of Turkey, where zeolite was thought to be the cause of malignant pleural mesothelioma and several other respiratory disorders. Expand
Prospective clinical and radiologic study of zeolite-exposed Turkish immigrants in Sweden.
TLDR
The comparatively low incidence of pleural lesions in the cohort is probably due to the low mean age (36 years), and further follow-up could give clues to the pathogenesis of malignant mesothelioma. Expand
Malignant mesothelioma due to environmental exposure to erionite: follow-up of a Turkish emigrant cohort.
TLDR
The incidence of malignant mesothelioma is extremely high in some Turkish villages where there is a low-level environmental exposure to erionite, a fibrous zeolite, and the risk is 135-times and 1-336-times greater in males and females than for the same sex and age groups in Sweden. Expand
An outbreak of pleural mesothelioma and chronic fibrosing pleurisy in the village of Karain/Urgüp in Anatolia.
TLDR
The 575 inhabitants of the remote Anatolian village of Karain suffered 11 deaths from pleural mesothelioma in 1975/76 and there were five cases of fibrosing pleurisy, but inhabitants of the neighbouring villages are free of mesotelioma. Expand
Environmental fiber-induced pleuro-pulmonary diseases in an Anatolian village: an epidemiologic study.
TLDR
Analysis of X-rays of the Tuzköy group revealed that subjects had calcified pleural plaques, pleural thickening, obscured costophrenic angles, and diffuse interstitial pulmonary fibrosis, which was considered to be responsible for the fiber-induced pleuro-pulmonary diseases in TuzKöy. Expand
MALIGNANT MESOTHELIOMA AND RADIOLOGICAL CHEST ABNORMALITIES IN TWO VILLAGES IN CENTRAL TURKEY An Epidemiological and Environmental Investigation
A comparative epidemiological and environmental study in two neighbouring villages, Karain and Karlin, in Central Turkey showed an excess adult mortality, shortening of life expectancy, and an excessExpand
Malignant mesothelioma in Turkish immigrants residing in Sweden.
TLDR
Mineralogical analysis of lung tissue specimens from two cases of malignant pleural mesothelioma revealed the presence of both zeolite and asbestos minerals and therefore suggested a synergistic effect involving both types of minerals. Expand
...
1
2
3
4
5
...