Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture

@article{Rheinwald1987MesosecrinAS,
  title={Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture},
  author={James G. Rheinwald and Jeffrey L. Jorgensen and W C Hahn and A J Terpstra and Thomas M. O'Connell and K K Plummer},
  journal={The Journal of Cell Biology},
  year={1987},
  volume={104},
  pages={263 - 275}
}
Human mesothelial cells, endothelial cells, and type II kidney epithelial cells growing in culture devote approximately 3% of their total protein synthesis to the production of an Mr approximately 46-kD, pI 7.1, secreted glycoprotein (designated Sp46). Fibroblasts make about 1/10th as much Sp46 as these cell types, and their synthesis is dependent upon hydrocortisone. Keratinocytes, urothelial cells, conjunctival epithelial cells, and mammary epithelial cells do not make detectable amounts of… CONTINUE READING