Mesoscopic and Macroscopic Models for Mesenchymal Motion

  title={Mesoscopic and Macroscopic Models for Mesenchymal Motion},
  author={Thomas Hillen},
In this paper mesoscopic (individual based) and macroscopic (population based) models for mesenchymal motion of cells in fibre networks are developed. Mesenchymal motion is a form of cellular movement that occurs in three-dimensions through tissues formed from fibre networks, for example the invasion of tumor metastases through collagen networks. The movement of cells is guided by the directionality of the network and in addition, the network is degraded by proteases. The main results of this… CONTINUE READING


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