Mesoscale infraslow spontaneous membrane potential fluctuations recapitulate high-frequency activity cortical motifs.

@article{Chan2015MesoscaleIS,
  title={Mesoscale infraslow spontaneous membrane potential fluctuations recapitulate high-frequency activity cortical motifs.},
  author={Allen W. Chan and Majid H. Mohajerani and Jeffrey M. LeDue and Yu Tian Wang and Timothy H. Murphy},
  journal={Nature communications},
  year={2015},
  volume={6},
  pages={7738}
}
Neuroimaging of spontaneous, resting-state infraslow (<0.1 Hz) brain activity has been used to reveal the regional functional organization of the brain and may lead to the identification of novel biomarkers of neurological disease. However, these imaging studies generally rely on indirect measures of neuronal activity and the nature of the neuronal activity correlate remains unclear. Here we show, using wide-field, voltage-sensitive dye imaging, the mesoscale spatiotemporal structure and… CONTINUE READING
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