13 Citations
Locomotor hypoactivity and motor disturbances--behavioral effects induced by intracerebellar microinjections of dopaminergic DA-D2/D3 receptor agonists.
- Biology, PsychologyPolish journal of pharmacology
- 2001
Preliminary results seem to indicate that bilateral injection of 7-OH-DPAT, a DA-D2/D3 receptor agonist, to lobule 9/10 of rat cerebellar cortex reduces spontaneous locomotor activity (hypolocomotor effects) and induces balance and motor coordination disturbances, respectively.
Differential effects of 7-OH-DPAT and apomorphine on hyperactivity induced by MK-801 (dizocilpine) in rats
- Biology, PsychologyNeuropharmacology
- 2005
Central effects of nafadotride, a dopamine D3 receptor antagonist, in rats. Comparison with haloperidol and clozapine.
- Biology, PsychologyPharmacological reports : PR
- 2005
The results of the study indicate that nafadotride, the dopamine D3 receptor antagonist, has a behavioral and biochemical profile of action different from that of haloperidol but partially similar to that of clozapine.
Effects of AMPA/kainate receptor blockade on responses to dopamine receptor agonists in the core and shell of the rat nucleus accumbens
- Biology, PsychologyPsychopharmacology
- 2000
The present results demonstrate differential interactions of AMPA receptor blockade with dopamine agonists in ”dopamine-intact” animals and lack of site-selective effects of (+)-SKF-38393 and of 7-OH-DPAT within NAS is not attributable to drug diffusion.
The role of dopamine D3 compared with D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in rats
- Biology, PsychologyPsychopharmacology
- 2003
The facilitatory influence of a “high” dose of PD128,907 upon locomotion is mediated by postsynaptic D2 receptors and, possibly, countered by their D3 counterparts, while selective blockade of D2 but not of D3 receptors alone suppresses motor function.
Role of dopamine D2-like receptors and their modulation by adenosine receptor stimulation in the reinstatement of methamphetamine seeking
- Biology, PsychologyPsychopharmacology
- 2018
These results demonstrate the sufficiency of dopamine D3 receptors to reinstate MA seeking that is inhibited when combined with adenosine A1 receptor stimulation.
NMDA or AMPA/kainate receptor blockade prevents acquisition of conditioned place preference induced by D2/3 dopamine receptor stimulation in rats
- Biology, PsychologyPsychopharmacology
- 2005
Acquisition of place conditioning induced by systemic administration of 7-OH-DPAT is blocked by systemic NMDA receptor antagonism by MK-801 or by the AMPA/kainate receptor antagonist NBQX microinjected into the NAS shell subregion.
Effect of antidepressant drugs administered repeatedly on the dopamine D3 receptors in the rat brain.
- Biology, PsychologyEuropean journal of pharmacology
- 1998
Dopamine receptor subtypes and ingestive behaviour.
- Psychology, Biology
- 1999
7-OH-DPAT reduced successive negative contrast leading to the proposal that D3 receptors may mediate relative as well as absolute reinforcer value, and may well have implications for the treatment of eating disorders.
References
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- Biology, PsychologyEuropean journal of pharmacology
- 1992
The putative dopamine D3 receptor agonist 7-OH-DPAT: lack of mesolimbic selectivity.
- Biology, ChemistryEuropean journal of pharmacology
- 1994
Behavioral and biochemical effects of the dopamine D3 receptor-selective ligand, 7-OH-DPAT, in the normal and the reserpine-treated rat.
- Biology, MedicineEuropean journal of pharmacology
- 1994
Locomotor activity following intra‐accumbens microinjections of dopamine D1 agonist SK&F 38393 in rats
- Biology, PsychologySynapse
- 1993
The data were supportive of the hypothesis that dose‐related locomotor activities elicited by microinjections of SK&F 38393 into the Acb are independently mediated by D1 receptors.
Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other “D-2-like” agonists
- Biology, PsychologyNeuropharmacology
- 1993
Modulation of cocaine self-administration in the rat through D-3 dopamine receptors.
- Biology, PsychologyScience
- 1993
Three dopamine receptor agonists had affinities for binding to the D-3 receptor that correlated highly with their relative potencies in decreasing cocaine self-administration in the rat at doses that were not by themselves reinforcing.
Biochemical and electrophysiological effects of 7‐OH‐DPAT on the mesolimbic dopaminergic system
- BiologySynapse
- 1995
The results suggest the possibility that stimulation of dopamine D2 receptors with 7‐OH‐DPAT mimic biochemical and electrophysiological actions previously ascribed to D2 autoreceptor stimulation; however the lack of selective D3 antagonist precludes any firm conclusion in this sense.
Dissociation of autoreceptor activation and behavioral consequences of low-dose apomorphine treatment
- Biology, PsychologyProgress in Neuro-Psychopharmacology and Biological Psychiatry
- 1991
Evidence that striatal synthesis-inhibiting autoreceptors are dopamine D3 receptors.
- Biology, ChemistryEuropean journal of pharmacology
- 1993
Dopamine D1 receptor family agonists, SK&F38393, SK&F77434, and SK&F82958, Differentially affect locomotor activities in rats
- Biology, ChemistryPharmacology Biochemistry and Behavior
- 1993