Mesoglycan and sulodexide act as stabilizers and protectors of fibroblast growth factors (FGFs).

@article{Tardieu1994MesoglycanAS,
  title={Mesoglycan and sulodexide act as stabilizers and protectors of fibroblast growth factors (FGFs).},
  author={Mich{\`e}le Tardieu and Marie Christine Bourin and Pascal Desgranges and Pascale Barbier and Denis Barritault and Jean Pierre Caruelle},
  journal={Growth factors},
  year={1994},
  volume={11 4},
  pages={291-300}
}
Heparin and heparan sulfate proteoglycans (HSPGs) stabilize FGFs which belong to heparin-binding growth factors (HBGFs) on active conformation. They also strongly potentiate their mitogenic activity on many cell types, and protect them against thermal denaturation and enzymatic degradation. In the present work we have tested two heparin-like substances named mesoglycan and sulodexide obtained from bovine intestinal mucosal extracts. These products are used as heparin, in various of therapeutic… CONTINUE READING