Mesial temporal sclerosis: pathogenesis and significance.

  title={Mesial temporal sclerosis: pathogenesis and significance.},
  author={Zhi-jian Liu and Mohamad A Mikati and Gregory L. Holmes},
  journal={Pediatric neurology},
  volume={12 1},
Mesial temporal sclerosis (MTS) is a common pathologic finding in patients with temporal lobe epilepsy. Rarely MTS can be detected in children during the first decade of life, but is not commonly found until adolescence. Although the etiology of MTS remains controversial, there is now a considerable amount of evidence demonstrating that MTS is both a result and a cause of seizures. Clinical studies suggest that prolonged seizures or complicated febrile seizures may result in MTS. A variety of… CONTINUE READING

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