Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance?

@article{Burr2013MesenchymalSC,
  title={Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance?},
  author={Stephen P. Burr and Francesco Dazzi and Oliver A Garden},
  journal={Immunology and cell biology},
  year={2013},
  volume={91 1},
  pages={
          12-8
        }
}
In recent years, mesenchymal stromal cells (MSCs) and regulatory T cells (Tregs) have both garnered significant interest from immunologists worldwide, not least because of the potential application of both cell types in the treatment of many chronic inflammatory and autoimmune diseases. Although both MSCs and Tregs can be considered immunosuppressive in their own right, the induction of Tregs by activated MSCs is now a well-publicised phenomenon; however, only recently have the mechanisms… CONTINUE READING
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