Mesenchymal stem cells from reaming material possess high osteogenic potential and react sensitively to bone morphogenetic protein 7.

@article{Hoellig2016MesenchymalSC,
  title={Mesenchymal stem cells from reaming material possess high osteogenic potential and react sensitively to bone morphogenetic protein 7.},
  author={Melanie Hoellig and Fabian Westhauser and K. E. Kornienko and Kai Xiao and Gerhard Schmidmaier and Zahra Amini Moghaddam},
  journal={Journal of applied biomaterials & functional materials},
  year={2016},
  volume={15 1},
  pages={
          e54-e62
        }
}
BACKGROUND Femoral material harvested using the Reamer-Irrigator-Aspirator (RIA) system is an alternative source for autogenous bone material in the treatment of non-unions, especially in combination with bone morphogenetic proteins (BMP). So far, there is no in vivo evidence of BMP-7 interacting with mesenchymal stem cells (MSCs) from RIA material (RIA-MSCs) and iliac crest autogenous bone (BMSCs). The aim of this study was to compare their osteogenic potential when stimulated with BMP-7 in… CONTINUE READING
BETA