Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia.

@article{Gupta2012MesenchymalSC,
  title={Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia.},
  author={Naveen Gupta and Anna Krasnodembskaya and Maria G. Kapetanaki and Majd Mouded and Xinping Tan and Vladimir B. Serikov and Michael A. Matthay},
  journal={Thorax},
  year={2012},
  volume={67 6},
  pages={533-9}
}
RATIONALE Bacterial pneumonia is the most common infectious cause of death worldwide and treatment is increasingly hampered by antibiotic resistance. Mesenchymal stem cells (MSCs) have been demonstrated to provide protection against acute inflammatory lung injury; however, their potential therapeutic role in the setting of bacterial pneumonia has not been well studied. OBJECTIVE This study focused on testing the therapeutic and mechanistic effects of MSCs in a mouse model of Gram-negative… CONTINUE READING
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NDM-1--a cause for worldwide concern.

The New England journal of medicine • 2010

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis

SH Mei, JJ Haitsma, CC DosSantos
Nat Med • 2009

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