Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells.

@article{Ruester2006MesenchymalSC,
  title={Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells.},
  author={Brigitte Ruester and Stephan Goettig and Ralf J Ludwig and Roxana Bistrian and Stefanie M{\"u}ller and Erhard Seifried and Jens Gille and Reinhard Henschler},
  journal={Blood},
  year={2006},
  volume={108 12},
  pages={3938-44}
}
To explore the initial steps by which transplanted mesenchymal stem cells (MSCs) interact with the vessel wall in the course of extravasation, we studied binding of human MSCs to endothelial cells (ECs). In a parallel plate flow chamber, MSCs bound to human umbilical vein ECs (HUVECs) similar to peripheral-blood mononuclear cells (PBMCs) or CD34(+) hematopoietic progenitors at shear stresses of up to 2 dynes/cm(2). This involved rapid extension of podia, rolling, and subsequent firm adhesion… CONTINUE READING

From This Paper

Topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…