Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma

@article{Aquino2010MesenchymalSC,
  title={Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma},
  author={Jorge B Aquino and Marcela F. Bolontrade and Mariana G. Garc{\'i}a and Osvaldo L. Podhajcer and Guillermo Daniel Mazzolini},
  journal={Gene Therapy},
  year={2010},
  volume={17},
  pages={692-708}
}
Mesenchymal stem (stromal) cells (MSCs) are a source of circulating progenitors that are able to generate cells of all mesenchymal lineages and to cover cellular demands of injured tissues. The extent of their transdifferentiation plasticity remains controversial. Cells with MSC properties have been obtained from diverse tissues after purification and expansion in vitro. These cellular populations are heterogeneous and under certain conditions show pluripotent-like properties. MSCs present… CONTINUE READING

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