Mesenchymal stem cell spheroids exhibit enhanced in-vitro and in-vivo osteoregenerative potential


BACKGROUND Mesenchymal stem cells (MSCs) are a favored cell source for regenerative medicine because of their multilinage potential. However, the conventional monolayer technique used to culture MSCs, inadequately overcomes their low differentiation capacity. Culture of MSCs in multicellular spheroids, more accurately mimics the in-vivo microenvironment… (More)
DOI: 10.1186/s12896-014-0105-9


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