Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages.

@article{Kim2009MesenchymalSC,
  title={Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages.},
  author={Jaehyup Kim and Peiman Hematti},
  journal={Experimental hematology},
  year={2009},
  volume={37 12},
  pages={1445-53}
}
OBJECTIVE Mesenchymal stem cells (MSCs) are capable of modulating the immune system through interaction with a wide range of immune cells. This study investigates the hypothesis that interaction of MSCs with macrophages could play a significant role in their antiinflammatory/immune modulatory effects. MATERIALS AND METHODS MSCs were derived from bone marrow and monocytes were isolated from peripheral blood of healthy donors. We cultured human monocytes for 7 days without any added cytokines… CONTINUE READING
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