Mesenchymal stem cell-based therapy for cartilage repair: a review

  title={Mesenchymal stem cell-based therapy for cartilage repair: a review},
  author={Hideyuki Koga and Lars Engebretsen and Jan E. Brinchmann and Takeshi Muneta and Ichiro Sekiya},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
Articular cartilage injury remains one of the major concerns in orthopaedic surgery. Mesenchymal stem cell (MSC) transplantation has been introduced to avoid some of the side effects and complications of current techniques. The purpose of this paper is to review the literature on MSC-based cell therapy for articular cartilage repair to determine if it can be an alternative treatment for cartilage injury. MSCs retain both high proliferative potential and multipotentiality, including chondrogenic… CONTINUE READING

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