Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms.

@article{Segers2006MesenchymalSC,
  title={Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms.},
  author={Vincent F M Segers and Ivan Van Riet and Luc Andries and Katrien Lemmens and Marc J. Demolder and Ann J M L De Becker and Mark M. Kockx and Gilles W. De Keulenaer},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={290 4},
  pages={H1370-7}
}
Circulating stem cells home within the myocardium, probably as the first step of a tissue regeneration process. This step requires adhesion to cardiac microvascular endothelium (CMVE). In this study, we studied mechanisms of adhesion between CMVE and mesenchymal stem cells (MSCs). Adhesion was studied in vitro and in vivo. Isolated 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate-labeled rat MSCs were allowed to adhere to cultured CMVE in static and dynamic conditions. Either… CONTINUE READING

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