Mesenchymal precursor cells in the blood of normal individuals

  title={Mesenchymal precursor cells in the blood of normal individuals},
  author={Nathan J. Zvaifler and Lilla Marinova-Mutafchieva and Gill Adams and Christopher J. Edwards and Jill Moss and Jan A Burger and Ravinder N. Maini},
  journal={Arthritis Research},
  pages={477 - 488}
STATEMENT OF FINDINGS: Mesenchymal precursor cells found in the blood (BMPCs) of normal persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf serum (FCS) without growth factors. They form cells with fibroblast-like and stromal morphology, which is not affected by eliminating CD34, CD3, or CD14 cells. Osteogenic supplements (dexamethasone, ascorbic acid, and beta-glycerophosphate) added to the culture inhibited fibroblast formation, and BMPCs assumed the… CONTINUE READING
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