Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1.

Abstract

Mesenchymal-epithelial transitions (MET) are crucial for vertebrate organogenesis. The roles of Rho family GTPases in such processes during actual development remain largely unknown. By electroporating genes into chick presomitic mesenchymal cells, we demonstrate that Cdc42 and Rac1 play important and different roles in the MET that generates the vertebrate… (More)

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@article{Nakaya2004MesenchymalepithelialTD, title={Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1.}, author={Yukiko Nakaya and Shinya Kuroda and Yuji T Katagiri and Kozo Kaibuchi and Yoshiko Takahashi}, journal={Developmental cell}, year={2004}, volume={7 3}, pages={425-38} }