Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis

@article{Wu2007MesenchymalSC,
  title={Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis},
  author={Yaojiong Wu and Liwen Chen and Paul G. Scott and Edward E. Tredget},
  journal={STEM CELLS},
  year={2007},
  volume={25}
}
Although chronic wounds are common, treatment for these disabling conditions remains limited and largely ineffective. In this study, we examined the benefit of bone marrow‐derived mesenchymal stem cells (BM‐MSCs) in wound healing. Using an excisional wound splinting model, we showed that injection around the wound and application to the wound bed of green fluorescence protein (GFP)+ allogeneic BM‐MSCs significantly enhanced wound healing in normal and diabetic mice compared with that of… 

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