Mesenchymal Stem Cells Enhance Nerve Regeneration in a Rat Sciatic Nerve Repair and Hindlimb Transplant Model

@inproceedings{Cooney2016MesenchymalSC,
  title={Mesenchymal Stem Cells Enhance Nerve Regeneration in a Rat Sciatic Nerve Repair and Hindlimb Transplant Model},
  author={Damon S. Cooney and Eric G. Wimmers and Zuhaib Ibrahim and Johanna Grahammer and Joani M. Christensen and Gabriel A. Brat and Lehao W. Wu and Karim A. Sarhane and Joseph Lopez and Christoph Wallner and Georg J. Furtm{\"u}ller and Nance Yuan and John Pang and Kakali Sarkar and W. P. Andrew Lee and Gerald Brandacher},
  booktitle={Scientific reports},
  year={2016}
}
This study investigates the efficacy of local and intravenous mesenchymal stem cell (MSC) administration to augment neuroregeneration in both a sciatic nerve cut-and-repair and rat hindlimb transplant model. Bone marrow-derived MSCs were harvested and purified from Brown-Norway (BN) rats. Sciatic nerve transections and repairs were performed in three groups… CONTINUE READING