Mesenchymal Stem Cells

@article{Caplan1991MesenchymalSC,
  title={Mesenchymal Stem Cells},
  author={Arnold I. Caplan},
  journal={Cartilage},
  year={1991},
  volume={1},
  pages={6 - 9}
}
  • A. Caplan
  • Published 1 September 1991
  • Biology
  • Cartilage
Bone and cartilage formation in the embryo and repair and turnover in the adult involve the progeny of a small number of cells called mesenchymal stem cells. These cells divide, and their progeny become committed to a specific and distinctive phenotypic pathway, a lineage with discrete steps and, finally, end‐stage cells involved with fabrication of a unique tissue type, e.g., cartilage or bone. Local cuing (extrinsic factors) and the genomic potential (intrinsic factors) interact at each… 

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