Mesenchymal Stem Cell: Does it Work in an Experimental Model with Acute Respiratory Distress Syndrome?

@article{Yilmaz2012MesenchymalSC,
  title={Mesenchymal Stem Cell: Does it Work in an Experimental Model with Acute Respiratory Distress Syndrome?},
  author={Sema Dereli Yilmaz and Nihal Inandiklioğlu and Dinçer Yildizdaş and Cansu Subaşi and Arbil Avci Acikalin and Yurdun Kuyucu and Ibrahim Bayram and Ali Topak and Atila Tanyeli and Gokhan Duruksu and Erdal Karaoz},
  journal={Stem Cell Reviews and Reports},
  year={2012},
  volume={9},
  pages={80-92}
}
We hypothesized that bone marrow-derived mesenchymal stem cells (BM-MSCs) would have a possible role in the treatment of acute respiratory distress syndrome (ARDS). ARDS disease model was developed in Wistar albino male rats by intratracheal instillation of physiological saline solution. Anesthezied and tracheotomized rats (n = 8) with ARDS were pressure-controlled ventilated. Isolated and characterized rat (r-) BM-MSCs were labeled with GFP gene, and introduced in the lungs of the ARDS rat… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects.

Proceedings of the National Academy of Sciences of the United States of America • 2003
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