Mesencephalic corticospinal atrophy predicts baseline deficit but not response to unilateral or bilateral arm training in chronic stroke.

@article{Globas2011MesencephalicCA,
  title={Mesencephalic corticospinal atrophy predicts baseline deficit but not response to unilateral or bilateral arm training in chronic stroke.},
  author={Christoph Globas and Judith M Lam and Weihong Zhang and Anuar Imanbayev and Benjamin Hertler and Clemens Becker and Jill Whitall and Sandy McCombe-Waller and Susumu Mori and Daniel F. Hanley and Andreas R{\"u}diger Luft},
  journal={Neurorehabilitation and neural repair},
  year={2011},
  volume={25 1},
  pages={81-7}
}
OBJECTIVE Stroke survivors with motor deficits often have pyramidal tract atrophy caused by degeneration of corticospinal fibers. The authors hypothesized that the degree of atrophy correlates with severity of motor impairment in patients with chronic stroke and predicts the response to rehabilitation training. METHODS They performed a post hoc analysis of 42 hemiparetic patients (>6 months) who had been randomized to either 6 weeks of bilateral arm training with rhythmic auditory cueing… CONTINUE READING