Mesencephalic astrocyte-derived neurotrophic factor enhances nigral ??-aminobutyric acid release:

@inproceedings{Zhou2006MesencephalicAN,
  title={Mesencephalic astrocyte-derived neurotrophic factor enhances nigral ??-aminobutyric acid release:},
  author={Chunyi Zhou and Cheng Xiao and John W. Commissiong and Kre{\vs}imir Krnjevi{\'c} and Jiang-hong Ye},
  year={2006}
}
Mesencephalic astrocyte-derived neurotrophic factor (MANF) -one of a new class of astrocyte-derived human proteins - selectively promotes the survival of dopamine neurons of the ventral midbrain. Using the whole-cell clamp technique, we looked for acute effects of MANF on γ-aminobutyric acid type A (GABA A ) receptor-mediated inhibitory postsynaptic currents (IPSCs) in dopamine neurons of the substantia nigra pars compacta of 6 to 15-day-old rats. In slices, MANF increased the amplitude of… CONTINUE READING