Merlin: hanging tumor suppression on the Rac.

@article{Sherman2001MerlinHT,
  title={Merlin: hanging tumor suppression on the Rac.},
  author={Larry S. Sherman and David H Gutmann},
  journal={Trends in cell biology},
  year={2001},
  volume={11 11},
  pages={442-4}
}
Cancer can result from any number of abnormalities in the control of cell-cycle progression, intracellular signaling and transduction of extracellular cues. Many insights into the crucial events that govern the regulation of cell growth have derived from studies of the gene products mutated in inherited cancer syndromes. Recent work on the neurofibromatosis 2 (NF2) tumor suppressor gene suggests that this negative growth regulator might function by modulating growth factor and extracellular… CONTINUE READING

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