Merkel cell polyomavirus in Merkel cell carcinoma of Italian patients

@inproceedings{Paolini2011MerkelCP,
  title={Merkel cell polyomavirus in Merkel cell carcinoma of Italian patients},
  author={Francesca Paolini and P. Tortori Donati and Ada Amantea and Stefania Bucher and Emilia Migliano and Aldo Venuti},
  booktitle={Virology Journal},
  year={2011}
}
Merkel cell carcinoma (MCC) is a rare but very aggressive human malignancy of elderly or immunosuppressed patients. Clonal integration of a new human polyomavirus, the Merkel cell polyomavirus (MCPyV), has been reported in MCC patients. The main objective of the study was the detection of MCPyV and viral expression in clinical samples of Italian patients who were diagnosed MCC. DNA and RNA were extracted from nine MCCs to detect the presence of MCPyV. Viral large T gene (LT1 and LT3), and viral… CONTINUE READING