Merkel cell carcinoma

@article{Andea2008MerkelCC,
  title={Merkel cell carcinoma},
  author={Aleodor A. Andea and Daniel G. Coit and Bijal Amin and Klaus J. Busam},
  journal={Cancer},
  year={2008},
  volume={113}
}
Currently, little is known regarding the potential prognostic value of histologic features in primary cutaneous neuroendocrine (Merkel cell) carcinomas (MCC). 
Merkel Cell Carcinoma
TLDR
This chapter summarizes the current knowledge regarding Merkel cell carcinoma epidemiology, pathogenesis, clinical features, histopathologic features, clinical staging, and prognosis.
Merkel cell carcinoma of the abdominal wall
TLDR
A case of Merkel cell carcinoma stage IIIB with bilateral inguinal lymphadenopathy that on FNAB showed metastatic deposits of the tumor.
Effect of Sentinel Lymph Node Biopsy and LVI on Merkel Cell Carcinoma Prognosis and Treatment
TLDR
The influences of sentinel lymph node biopsy and lymphovascular invasion on treatment planning and prognosis for Merkel cell carcinoma are evaluated.
Recurrence after complete resection and selective use of adjuvant therapy for stage I through III Merkel cell carcinoma
TLDR
The authors describe their experience with a large cohort of patients who were treated at a single institution to describe patterns of recurrence after curative therapy.
Merkel cell carcinoma: what we know now
TLDR
Light is shed on this rare skin cancer and the latest advances in research regarding MCC are introduced, which can be effectively treated by surgery with or without postoperative radiation therapy.
Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
TLDR
Clinical, histopathological and immunhistochemical features of Merkelcell carcinoma are reported and the role of Merkel cell polyomavirus is discussed.
Management of Merkel Cell Carcinoma
TLDR
This review discusses therapeutic options by disease stage and highlights where questions remain to be answered in Merkel cell carcinoma.
Merkel cell carcinoma: current status of targeted and future potential for immunotherapies.
TLDR
Better understanding of the molecular pathways of infection and carcinogenesis has provided potential molecular targets and potential immunotherapies which are discussed in this review.
Merkel Cell Carcinoma
TLDR
This is the second reported case of a metastatic MCC to the stomach presenting as upper gastrointestinal bleeding and the first case confirmed by the newer immunohistochemical techniques.
Merkel cell carcinoma.
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References

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Merkel cell carcinoma: Changing incidence trends
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  • Medicine
    Journal of surgical oncology
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The objective of this study was to define the incidence trends of Merkel cell carcinoma (MCC), a rare and aggressive cutaneous malignancy.
Merkel cell carcinoma: a clinicopathological study of 11 cases
TLDR
The 12‐year experience with Merkel cell carcinomas from a clinical and pathological point of view is reported.
Merkel cell carcinoma
The purpose of the current study was to determine the outcomes of patients with previously untreated Merkel cell carcinoma of the skin who were treated with curative intent.
Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study
Background: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor arising predominantly on sun‐exposed skin of older and usually immunosuppressed individuals.
Clinicopathological and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers
Aims:  To evaluate the clinicopathological and immunohistochemical characteristics of Merkel cell carcinoma (MCC) in an attempt to find new, potentially significant, prognostic markers.
Chemotherapy for patients with locally advanced or metastatic Merkel cell carcinoma
TLDR
Merkel cell carcinoma is a highly malignant skin neoplasm that occurs in 20–52% of patients and the role of chemotherapy in the treatment of patients with this rare tumor is unclear.
Intraoperative lymphatic mapping and sentinel lymph node biopsy for Merkel cell carcinoma
TLDR
The feasibility of identifying the sentinel node in patients with clinically node‐negative Merkel cell carcinoma was evaluated.
Prognostic value of tumor thickness in patients with merkel cell carcinoma
TLDR
The purpose of this study was to see if depth of tumor invasion would predict prognosis independent of tumor stage, and hypothesized that tumor thickness might correlate with both regional and metastatic tumor spread.
Merkel cell carcinoma of the head and neck: Is adjuvant radiotherapy necessary?
TLDR
The primary aim of this study was to determine whether combined treatment with surgery and radiotherapy improves outcome in a multi‐institutional cohort of patients with Merkel cell carcinoma of the head and neck.
Immunohistochemical analysis of sentinel lymph nodes from patients with Merkel cell carcinoma
Immunohistochemical analysis of sentinel lymph nodes from patients with breast carcinoma and melanoma has been shown to increase the sensitivity for detecting lymph node metastases. To the authors'
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