Merkel Cell Carcinoma: Review

@article{Pulitzer2009MerkelCC,
  title={Merkel Cell Carcinoma: Review},
  author={M. Pulitzer and B. Amin and K. Busam},
  journal={Advances in Anatomic Pathology},
  year={2009},
  volume={16},
  pages={135-144}
}
Merkel cell carcinoma (MCC) is synonymous with primary cutaneous neuroendocrine carcinoma. It tends to affects elderly whites, but there is also an increased incidence among immunosuppressed patients. The recent identification of a novel polyomavirus associated with the tumor has stimulated renewed interest in its pathogenesis. MCC tends to show classic histologic features of a neuroendocrine carcinoma and is often positive for CK20, but nonclassic cytologic findings and unusual… Expand
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What is known and what is still controversial about the histogenesis, diagnosis, and management of Merkel cell carcinoma and the structure and function of the Merkel cell from which it is believed to be derived are addressed. Expand
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