Mercury induces the expression of cyclooxygenase-2 and inducible nitric oxide synthase

@article{Park2013MercuryIT,
  title={Mercury induces the expression of cyclooxygenase-2 and inducible nitric oxide synthase},
  author={Hye-jeong Park and Hyung-Sun Youn},
  journal={Toxicology and Industrial Health},
  year={2013},
  volume={29},
  pages={169 - 174}
}
Nuclear factor-κB (NF-κB) is a transcription factor that mediates the inducible expression of a variety of genes involved in immune and inflammatory responses. NF-κB activation induces numerous proinflammatory gene products including cytokines, cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS). The divalent heavy metal mercury has been used for thousands of years. Although mercury is clearly toxic to most mammalian organ systems, especially the immune system, exposure has… 
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