Mercury Toxicity and Systemic Elimination Agents

  title={Mercury Toxicity and Systemic Elimination Agents},
  author={Joseph M. Mercola and Dietrich K. Klinghardt},
  journal={Journal of Nutritional \& Environmental Medicine},
This paper reviews the published evidence supporting amalgam toxicity and clinical techniques that facilitate mercury elimination. A literature review is provided which documents effective mercury elimination strategies to improve mercury toxicity syndromes. Considering the weight of evidence supporting mercury toxicity, it would seem prudent to select alternative dental restoration materials and consider effective mercury elimination strategies if mercury toxicity is present. 

Integrative Medicine Approach To Peripheral Neuropathy-Avoiding Pitfalls Of Ineffective Current Standards In Assessing Chronic Low-Grade Mercury Toxicity And Functional Musculoskeletal Lesions.

This patient's chronic mercury toxicity from dental amalgams was effectively treated using a functional medicine approach to care and a 70% decrease in total blood mercury levels and a dramatic improvement of all her symptoms.

Evaluation of mercury adsorption and removal efficacy of pulverized Chlorella (C. vulgaris)

Chlorella is a green alga consumed as dietary food supplement in pulverized form. In addition to its high nutritional value, it is reported as an excellent detoxifying agent. Pulverized Chlorella has

Evaluation of Chlorella as a Decorporation Agent to Enhance the Elimination of Radioactive Strontium from Body

Results indicated that Chlorella could inhibit the absorption of 90Sr into the blood and enhance the elimination of 90sr from the body through adsorption in intestine.

IAOMT ACCREDITATION-- Checklist for Completing Unit 4: Clinical Nutrition and Heavy Metal Detoxification for Biological Dentistry

  • Medicine
  • 2020
An analysis of the literature shows that vitamin D plays a significant role in maintaining healthyperiodontal and jaw bone tissues, alleviating inflammation processes, stimulating post-operative healing of periodontal tissues and the recovery of clinical parameters, however, further research is needed to clarify the required vitamin D concentration in plasma before starting periodontic treatment.

Biochemical evidence on the potential role of methyl mercury in hepatic glucose metabolism through inflammatory signaling and free radical pathways

It is highlighted that activity of key enzymes involved in glucose metabolism is changed, owing to MeHg induced toxicity in the liver, which caused a significant reduction in antioxidant markers like ferric reducing antioxidant power and total thiol molecules.


It is proposed that: increasing duration and number of amalgam fillings might in fact be capable of decreasing cholinergic activity whereas only slightly changes in adrenergic activity.

Metal concentrations and potential health risk in clam (Meretrix lyrata Sowerby 1851) tissues from East Java Coast, Indonesia

The presence of Hg, Cu, Cr, Cd, Pb, and Zn in clam from the East Java Coast (EJC), Indonesia, is reported, indicating that these metals could be harmful to consumers (particularly non-carcinogenic impacts).

Harmful Interactions of Non-Essential Heavy Metals with Cells of the Innate Immune System

This review is focused on the pro-oxidative/pro-inflammatory interactions of non-essential heavy metals with the cells of the innate immune system, a somewhat under-appreciated mechanism of metal induced toxicity.

Protective effect of lycopene against mercury-induced cytotoxicity in albino mice: pathological evaluation.

In vivo results showed that the lycopene supplementation decreases cytotoxicity induced by mercury and its protective role is dose-dependent and weight gain increased depending on dose of applied lycopenes.

A follow-up study of patients with subjective symptoms related to dental materials.

At the group level, the intensity of local and some general subjective symptoms was reduced after replacement of the materials, but not to the level found in the general population.



Treatment of mercury intoxication.

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  • Chemistry
    Current opinion in pediatrics
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Although dimercaprol is contraindicated in organic mercury exposures, meso-2,3-dimercapto-1-propanesulfonate may be used to chelate all species of mercury.

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Comparisons between subjects with and without amalgam showed significant differences in subjective reports of mental health, suggesting that inorganic mercury poisoning from dental amalgam does affect the mind and emotions.

Chronic elemental mercury intoxication: clinical and field studies in lampsocket manufacturers.

It is concluded that recovery from chronic elemental mercury intoxication may be complete when patients are removed early from the exposure environment.

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  • Chemistry
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Therapies for assisting the reduction of a mercury load include the use of 2,3-dimercaptosuccinic acid (DMSA) and 2,1-propanesulfonic acid ( DMPS), and additional supplementation to assist in the removal of mercury and to reduce its adverse effects is discussed.

Zinc protection of mercury-induced hepatic toxicity in mice.

The results of this experiment indicate that Hg has a toxic effect on liver, while Zn has a protective action against such toxic effects.

Evaluation of the safety issue of mercury release from dental fillings

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  • Medicine
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology
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On the basis of present data, medical researchers do not make any claims that amalgam mercury is the cause of a specific disease, but experimental pathophysiological evidence in sheep and primate models leads us to conclude that human health consequences might result from continuous exposure to mercury at levels released from mercury fillings.

Human exposure to mercury and silver released from dental amalgam restorations.

In 35 healthy individuals, the number of amalgam surfaces was related to the emission rates of mercury into the oral cavity and to the excretion rate of mercury by urine, and a high interplay between the variables was exhibited.

Iatrogenic exposure to mercury after hepatitis B vaccination in preterm infants.

Comparison of pre- and post-vaccination mercury levels showed a significant increase in both preterm and term infants after vaccination, which was significantly higher in preterm infants as compared with term infants.

Mercury exposure from “silver” tooth fillings: emerging evidence questions a traditional dental paradigm

Animal and human experiments demonstrate that the uptake, tissue distribution, and excretion of amalgam Hg is significant, and that dental amalgam is the major contributing source to Hg body burden in humans.

Diagnostic Value of a Chelating Agent in Patients with Symptoms Allegedly Caused by Amalgam Fillings

The present DMPS challenge test did not differentiate between patients with or those without complaints self-related to their amalgam fillings but did confirm the higher mercury values in patients with dental amalgam.