Mercury Intoxication: It Still Exists

  title={Mercury Intoxication: It Still Exists},
  author={Carolyn E. Beck and Bernice R. Krafchik and Jeffrey Traubici and Sheila J Jacobson},
  journal={Pediatric Dermatology},
Abstract:  A 3‐year‐old boy presented to the Hospital for Sick Children with systemic symptoms and oropharyngeal and peripheral extremity changes suggestive of Kawasaki disease. He was found to have severe hypertension. Investigation for a catecholamine‐secreting tumor was negative. Toxins were considered when the patient's 20‐month‐old brother presented with similar symptoms, and the boys were subsequently diagnosed with elemental mercury poisoning. We review the literature on mercury… 
Mercury Poisoning as a Kawasaki Mimic: Case Report and Review of Literature -
A previously healthy 5 year-old male presented to his pediatrician with intermittent high fevers, agitation, myalgias, and a “sandpaper-like” rash, which was initially a maculopapular, erythematous eruption with truncal distribution and subsequent cephalo-caudal progression.
Mercury Intoxication: Lack of Correlation Between Symptoms and Levels
The case of an 8-year-old boy with history of mercury exposure, signs and symptoms suggestive of mercury intoxication, and good response to chelation therapy, but with only mild increase in urinary mercury levels is reported.
Mercury poisoning in two 13-year-old twin sisters
In a patient with any kind of bone and joint pain, skin rash erythema and peripheral neuropathy, mercury poisoning should be considered as a differential diagnosis.
Metallic mercury vapour poisoning revisited
A 40‐year‐old woman and her two children were hospitalized with a 1‐week history of a generalized lichenoid eruption; however, on returning home, features of acrodynia with digital gangrene developed in the woman, leading to suspicion of heavy metal poisoning.
Metal mercury poisoning in two boys initially treated for brucellosis in Mashhad, Iran
Two brothers who presented with pain in their lower extremities, sweating, salivation, weight loss, anorexia and mood changes on admission are reported to emphasize the importance of acrodynia as a differential diagnosis for brucellosis in endemic areas.
Elemental mercury intoxication in 7 patients admitted to a pediatric rheumatology clinic.
It is emphasized that mercury intoxication should be kept in mind with unexplained extremity pain and timely diagnosis and treatment may prevent severe morbidity and mortality.
Elemental mercury exposure: An evidence-based consensus guideline for out-of-hospital management
This guideline is to assist poison center personnel in the out-of-hospital triage and initial management of patients with suspected exposures to elemental mercury.
An epidemiological analysis of the 'autism as mercury poisoning' hypothesis
The evidence for a causal relationship between autism and mercury is compelling and analogous to epidemiological evidence of the smoking–lung cancer relationship, a mercury–autism relationship is confirmed.
Rethinking treatment of mercury poisoning: the roles of selenium, acetylcysteine, and thiol chelators in the treatment of mercury poisoning: a narrative review
A combined approach for mercury poisoning treatment was developed focusing on restoration of selenoprotein function, reduction of oxidative stress and increased mercury elimination, and how the different forms of mercury are impacted by use of chelation and selenium.


Mercury intoxication presenting with hypertension and tachycardia
Mercury intoxication should be considered in the differential diagnosis of hypertension with tachycardia even in patients presenting without the skin lesions typical of mercury intoxication and without a history of exposure.
Mercury Intoxication and Arterial Hypertension: Report of Two Patients and Review of the Literature
Two children in the same household with symptomatic arterial hypertension simulating pheochromocytoma were found to be intoxicated with elemental mercury, and elevated catecholamines were demonstrated in plasma and urine.
Mercury intoxication presenting with tics
A 5 year old Chinese boy presented with recurrent oral ulceration followed by motor and vocal tics. The Chinese herbal spray he used for his mouth ulcers was found to have a high mercury content. His
Adverse mercurial reactions in the form of acrodynia and related conditions.
None of the above symptoms is alone diagnostic for the disease, and opinions differ concerning the cardinal changes of acrodynia.
Clinical quiz
A 14-year-old boy, with deafness, was referred for assessment because his father had a history of deafness and renal failure and IVP showed that both kidneys had dysmorphic pelvicalyceal systems.
Treatment of mercury intoxication.
  • C. Baum
  • Chemistry
    Current opinion in pediatrics
  • 1999
Although dimercaprol is contraindicated in organic mercury exposures, meso-2,3-dimercapto-1-propanesulfonate may be used to chelate all species of mercury.
Mercury--an element of mystery.
  • T. Clarkson
  • Physics, Psychology
    The New England journal of medicine
  • 1990
A single case of acrodynia led to the investigation described by Agocs et al and the discovery that many more children had been exposed to mercury but did not con...