Mercurial reagents inhibit flow through ADH-induced water channels in toad bladder.

@article{Hoch1989MercurialRI,
  title={Mercurial reagents inhibit flow through ADH-induced water channels in toad bladder.},
  author={Brian S. Hoch and Philip C. Gorfien and Drew A. Linzer and Mario A. Fusco and Sherman D. Levine},
  journal={The American journal of physiology},
  year={1989},
  volume={256 5 Pt 2},
  pages={
          F948-53
        }
}
Mercurial reagents inhibit the water permeability of erythrocytes and proximal renal tubule. We examined the effect of two such agents on vasopressin-induced water transport across toad urinary bladder. Water flows were measured in unfixed tissues and in tissues fixed either with N-ethylmaleimide (NEM) or with glutaraldehyde. When added concurrently with 20 mU/ml vasopressin, 1 mM mucosal p-chloromercuribenzene-sulfonic acid (p-CMBS) inhibited water flow within 1 h. p-CMBS also inhibited flow… CONTINUE READING
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