Mephedrone and methylenedioxypyrovalerone (MDPV), major constituents of “bath salts,” produce opposite effects at the human dopamine transporter

@article{Cameron2013MephedroneAM,
  title={Mephedrone and methylenedioxypyrovalerone (MDPV), major constituents of “bath salts,” produce opposite effects at the human dopamine transporter},
  author={Krasnodara N Cameron and Renata Kolanoś and Rakesh Verkariya and Louis J. De Felice and Richard A Glennon},
  journal={Psychopharmacology},
  year={2013},
  volume={227},
  pages={493-499}
}
Psychoactive “bath salts” represent a relatively new drug of abuse combination that was placed in Schedule I in October 2011. Two common ingredients of bath salts include the cathinone analogs: mephedrone and methylenedioxypyrovalerone (MDPV). The mechanism of action of these synthetic cathinone analogs has not been well investigated. Because cathinone and methcathinone are known to act as releasing agents at the human dopamine transporter (hDAT), mephedrone and MDPV were investigated at hDAT… CONTINUE READING
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