Meperidine: A Critical Review

@article{Latta2002MeperidineAC,
  title={Meperidine: A Critical Review},
  author={Kenneth S Latta and B. Ginsberg and R. Barkin},
  journal={American Journal of Therapeutics},
  year={2002},
  volume={9},
  pages={53-68}
}
  • Kenneth S Latta, B. Ginsberg, R. Barkin
  • Published 2002
  • Medicine
  • American Journal of Therapeutics
  • Meperidine was initially synthesized as an anticholinergic agent but was soon discovered to have analgesic properties. Although meperidine's anticholinergic effects were demonstrated in vivo, the anticholinergic effects on the biliary and renal tracts have not been demonstrated in vivo. Studies have clearly demonstrated that meperidine is no more efficacious in treating biliary or renal tract spasm than comparative mu opioids. The initial studies demonstrating the analgesic efficacy of… CONTINUE READING

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