Menstruation as a Defense Against Pathogens Transported by Sperm

@article{Profet1993MenstruationAA,
  title={Menstruation as a Defense Against Pathogens Transported by Sperm},
  author={Margie Profet},
  journal={The Quarterly Review of Biology},
  year={1993},
  volume={68},
  pages={335 - 386}
}
  • M. Profet
  • Published 1 September 1993
  • Biology, Medicine
  • The Quarterly Review of Biology
Sperm are vectors of disease. During mammalian insemination bacteria from the male and female genitalia regularly cling to sperm tails and are transported to the uterus. I propose that menstruation functions to protect the uterus and oviducts from colonization by pathogens. Menstrual blood exerts mechanical pressure on uterine tissue, forcing it to shed, and delivers large numbers of immune cells throughout the uterine cavity, directly combating pathogens. The mechanisms of menstruation show… 
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