Menstrual cycle worsening of epileptic seizures in women with symptomatic focal epilepsy.

@article{Bazn2005MenstrualCW,
  title={Menstrual cycle worsening of epileptic seizures in women with symptomatic focal epilepsy.},
  author={Ana Carolina Belini Baz{\'a}n and M. Montenegro and F. Cendes and L. L. Min and C. Guerreiro},
  journal={Arquivos de neuro-psiquiatria},
  year={2005},
  volume={63 3B},
  pages={
          751-6
        }
}
INTRODUCTION Hormonal fluctuation is responsible for worsening of epileptic seizures during the menstrual cycle. OBJECTIVE To identify irregularities in the menstrual cycles of women with mesial temporal lobe epilepsy (MTLE) and extratemporal focal epilepsy (ETFE) and correlate the frequency of seizures during the menstrual cycles. METHOD We evaluated prospectively women in the menacme with MTLE and ETFE. Calendars were provided for these patients, and they were asked to mark their seizure… Expand
Seizure exacerbation and hormonal cycles in women with epilepsy
TLDR
Seizure frequencies were greater during menstrual and ovulatory phases for ovulatory cycles, and during non-menstrual phases for anovulatory cycles. Expand
Catamenial Epilepsy: The Menstrual Cycle as a Clue to Predict Future Refractory Seizures.
TLDR
It is important for the emergency physician to consider catamenial epilepsy in the differential diagnosis for secondary causes of seizure to ensure appropriate follow-up, as well as improve the quality of life of patients suffering from uncontrolled seizures. Expand
Progesterone therapy in women with epilepsy.
TLDR
Progesterone combined with antiepileptic therapy was well tolerated and resulted in a significant reduction of seizure frequency in majority of patients with catamenial epilepsy. Expand
CATAMENIAL EPILEPSY: FASCINATING INCIDENT IN EPILEPTOLOGY
TLDR
The aim of this article is to report the effects of sex hormones on epilepsy and to describe treatment approaches for catamenial epilepsy. Expand
Progesterone therapy in women with intractable catamenial epilepsy
TLDR
Progesterone effectiveness as a complementary treatment in women with intractable catamenial epilepsy has a significant effect on the degree of decreasing in the number of the seizures. Expand
Management of Libyan Patients with Catamenial Epilepsy
This study was conducted to assess in Libyan females the incidence of catamenial epilepsy. This form of epilepsy is defined as the increase in seizure frequency in relation to the menstrual cycle. WeExpand
Catamenial epilepsy: hormonal aspects
TLDR
Investigation has demonstrated the existence of at least three patterns of catamenial seizure exacerbation: perimenstrual and periovulatory in ovulatory cycle and entire luteal phase in anovulatory cycle. Expand
Interictal spike frequency varies with ovarian cycle stage in a rat model of epilepsy
TLDR
It is concluded that the estrous cycle entrains IIS in the modified KA and pilocarpine SE models of epilepsy, suggesting that the ovarian cycle influences more aspects of epilepsy than seizure susceptibility. Expand
Seizure burden fluctuates with the female reproductive cycle in a mouse model of chronic temporal lobe epilepsy
TLDR
The results suggest that the stages of proestrus and estrus are associated with higher seizure burden in IHKA mice, which may recapitulate at least some aspects of reproductive cycle-associated seizure clustering. Expand
The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy
TLDR
There is emerging evidence that endogenous neurosteroids with anticonvulsant or proconvulsant effects could play a critical role in catamenial epilepsy, which has not been successfully treated with conventional antiepileptic drugs. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 42 REFERENCES
Reproductive Endocrine Disorders in Women with Primary Generalized Epilepsy
TLDR
The hormonal alterations observed in the patients with normal menstrual cycles seem to support the hypothesis that a neurotransmitter dysfunction might be the common pathogenetic mechanism resulting in both REDs and PGE. Expand
Premenstrual seizure increase: influence of age, duration of disease, seizure frequency, previous complaint of perimenstrual accentuation, EEG and CT scan findings.
TLDR
The findings suggest that the female sexual hormones alter cerebral excitability when there is an underlying structural pathology shown by CT scan or an electrical cerebral dysfunction revealed by EEG. Expand
Período ovulatório e crises epilépticas
We prospectively follow up 80 mentally healthy women at menacme age, with chronic epilepsy and had had least one seizure in the month preceding the study. We selected 59 patients from whom we wereExpand
Predictors of ovulatory failure in women with epilepsy
TLDR
Women with epilepsy are more likely to experience anovulatory menstrual cycles and the effects of epilepsy syndrome, and AED therapy may be additive, and clinicians must be alert to this potential complication of epilepsy. Expand
Menstrual cycle interval and ovulation in women with localization-related epilepsy
In an investigation of 100 women with localization-related epilepsy, anovulatory cycles were significantly greater in proportion in women with 21–25 or 33–35 day cycles (Group B) and in women withExpand
Long-term reproductive endocrine health in young women with epilepsy during puberty
TLDR
Epilepsy during pubertal maturation does not affect reproductive endocrine health in female subjects who discontinue the medication before adulthood, however, an increased prevalence of endocrine disorders is detected if the patients remain on antiepileptic drugs, especially VPA, until adulthood. Expand
EPILEPTIC SEIZURES IN WOMEN RELATED to PLASMA ESTROGEN and PROGESTERONE DURING the MENSTRUAL CYCLE
TLDR
Nine periods in seven women with partial epilepsy have been investigated with respect to frequency of fits, and estrogen‐progesterone levels in blood plasma, and a positive correlation between the number of secondary generalized seizures and the mean estrogen/progestersterone ratios. Expand
INÍCIO DE CRISES EPILÉPTICAS NA MENARCA
TLDR
Nine patient whose epileptic seizures had began in the menarche phase were studied and it was concluded that the observation of a larger number of patients is necessary to confirm these data. Expand
Temporal lobe epilepsy. Follow-up investigation of 74 temporal lobe resected patients.
TLDR
The social rehabilitation was found to be significantly improved by operation at an early age and the more specific and circumscribed the histological abnormality the better the final outcome. Expand
Catamenial epilepsy: clinical aspects.
TLDR
Evidence from animal experiments and studies in humans have demonstrated an ovarian steroid hormone effect on neuronal excitability, supporting a biologic basis for this fluctuation in seizure frequency in women with epilepsy. Expand
...
1
2
3
4
5
...